Web30 jul. 2024 · Helmed by lead author Joanna Moncrieff, a professor of psychiatry at University College London, the study was an umbrella review of research into selective … Web20 jul. 2024 · These findings together led the authors to conclude that there is “no support for the hypothesis that depression is caused by lowered serotonin activity or concentrations.” The researchers say their findings are important as studies show that as many as 85-90% of the public believes that depression is caused by low serotonin or a …
Part two: response to criticism of our chemical imbalance paper
Web20 jul. 2024 · For three decades, people have been deluged with information suggesting that depression is caused by a “chemical imbalance” in the brain – namely an imbalance of a brain chemical called serotonin. However, our latest research review shows that the evidence does not support it. Web3 sep. 2024 · Moncrieff and colleagues also reviewed studies of various receptors and genes connected to the serotonin system and once again did not find any evidence supporting the simplistic serotonin hypothesis. swaddles newborn
Frontiers Is the serotonin hypothesis dead? If so, how will clinical ...
Web19 jul. 2024 · Although “the serotonin hypothesis of depression is still influential,” Moncrieff and coauthors noted, citing widely adopted textbooks published as recently as 2024 and surveys indicating that ... Web22 jul. 2024 · In this work, Joanna Moncrieff and colleagues conduct the first comprehensive review that synthesizes the relevant evidence to examine the serotonin hypothesis of depression. Umbrella reviews are one of the most effective ways of synthesizing information, as they involve the review of systematic reviews and meta … Web15 feb. 2024 · The umbrella review by Moncrieff et al. summarizes the results of all systematic reviews and meta-analyses on the serotonin hypothesis of depression and … swaddles organic farm