Cisplatin with rt

Author: mcro

August undefined, 2024

WebThe beneficial effects of cisplatin, which is the most widely used agent for CCRT in CC patients, whether alone or in combination with other drugs, were not independently … WebApr 12, 2024 · The patient was started on gemcitabine, cisplatin, and nanoparticle albumin-bound paclitaxel (nab-paclitaxel). After 3 months of chemotherapy, the patient's AFP increased to 43.8 ng/ml and her CA 19-9 increased to 21.4 U/ml. On repeat CT scan, the size of the tumor was stable, but there was suspected intraductal extension toward the …

Cisplatin Chemoradiotherapy vs Radiotherapy in FIGO …

WebApr 1, 2024 · Cisplatin Chemoradiotherapy vs Radiotherapy in FIGO Stage IIIB Squamous Cell Carcinoma of the Uterine Cervix: A Randomized … WebJun 29, 2011 · Cisplatin is the most common agent used in combination with RT, and is one of the best studied. The standard regimen is three-weekly high-dose (100 mg/m 2) cisplatin (three cycles) concurrent with RT ( 2, 3 ). However, cisplatin at a dose of 100 mg/m 2 with concomitant RT is associated with significant acute and late toxicities ( 2, 4, … floor mounted vice

Cervical Cancer Treatment Regimens - Cancer Therapy Advisor

WebFeb 16, 2016 · Cisplatin is standardly dosed in a three-weekly schedule of 100 mg/m 2 (total dose 300 mg/m 2) combined with standard RT [3,6,7,9,10]. However, a high-dose cisplatin regimen is associated with major toxic side effects (myelosuppression, neurotoxicity, ototoxicity, and nephrotoxicity). WebIn addition, no significant difference in overall survival was seen in the matched cohorts. ChemoRT with either cisplatin or carboplatin was superior to RT alone and RT with concurrent cetuximab. In the multivariable model, the adjusted hazard ratio of CSM for carboplatin relative to cisplatin was 1.01 (95% CI, 0.79–1.28; P=.94). Web1 day ago · Combined treatment with idronoxil and cisplatin enhances tumor response in humanized mice model. ... (Qiagen) according to the manufacturer's instructions. Total RNA (500 ng) was reversed transcribed with Primescript RT (Takara), with the cDNA serving as the template for amplification. Quantitative real-time PCR was subsequently performed … great place to work certification parameters

High-Dose Cisplatin for Head and Neck Cancer Lives On

Safety and efficacy of concurrent carboplatin plus radiotherapy for ...

WebJan 25, 2016 · Arm A represents concurrent pemetrexed-cisplatin (Pem-Cis) and thoracic radiation therapy (TRT) followed by consolidation pemetrexed. Arm B represents concurrent etoposide-cisplatin (Eto-Cis) and TRT followed by one of three consolidation chemotherapy regimens of choice: Eto-Cis, vinorelbine-cisplatin (Vin-Cis), or paclitaxel-carboplatin … WebSep 21, 2016 · RTOG 88-08 used a chemoradiotherapy regimen of cisplatin 100 mg/m 2 on days 1 and 29 and vinblastine 5 mg/m 2 once per week for 5 consecutive weeks beginning on day 1, followed by TRT to a total dose of 60 Gy in … floor mounted urinals for saleWebIntroduction. Radiotherapy (RT) is the most common type of curative and palliative treatment for all cancer patients, including breast cancer patients. 1,2 Worldwide, breast cancers had totaled up to 2 million new cancer cases in the year 2024, which was approximately closed to the number of lung cancers and followed by colorectal, prostate and stomach cancers. … great place to work certified 2019

"WebSep 18, 2024 · NCBI Bookshelf " - Cisplatin with rt

Cisplatin with rt

Low-Dose Weekly vs High-Dose Cisplatin - Full Text View ...

WebThe TPF triplet regimen (docetaxel, cisplatin, and 5‐FU) has a trend of further improving treatment efficacy compared with the traditional doublet regimen. 35 , 36 In a phase II study, concurrent chemoradiotherapy with TPF achieved a clinical CR rate of 52.4%, much higher than the previously reported CR rate of 20%. 9 However, the high ... WebThe beneficial effects of cisplatin, which is the most widely used agent for CCRT in CC patients, whether alone or in combination with other drugs, were not independently reported in the CCCMAC study. 37 Our study focused on the comparisons between DDP-CCRT and exclusive RT to form a definitive conclusion for this issue. Moreover, only patients ...

Did you know?

WebMar 1, 2024 · In the weekly arm, cisplatin was administered at 40 mg/m 2 once a week for seven cycles during the RT period. Criteria for dose reduction or delay were … WebApr 14, 2024 · Among the extracellular vesicles, apoptotic bodies (ABs) are only formed during the apoptosis and perform a relevant role in the pathogenesis of different diseases. Recently, it has been demonstrated that ABs from human renal proximal tubular HK-2 cells, either induced by cisplatin or by UV light, can lead to further apoptotic death in …

WebBackground and purpose: In patients with head-and-neck cancer treated with chemoradiotherapy (CRT), a cisplatin-based regimen is often used. Several treatment schedules are accepted with a cumulative cisplatin dose of 200 mg/m (2) (CisCD200) given during radiotherapy. WebFeb 11, 2024 · Cisplatin was given either at a dose of 100 mg/m 2 every 3 weeks (day 1, 22, and 43) during RT (University Hospital Basel) to a planned cumulative dose of 300 mg/m 2 or at a dose of 40 mg/m 2 (University Hospital Zurich) or 50 mg/m 2 (Cantonal Hospital Winterthur) weekly for 6 or 7 infusions (days 1, 8, 15, 22, 29, 36, and 43) to a planned …

WebSep 15, 2024 · DESCRIPTION. Cisplatin Injection (cisplatin injection (cisplatin (cisplatin injection) injection) ) is a sterile aqueous solution, available in 50, 100 and 200 mL … WebCisplatin is a platinum-based agent whose nephrotoxicity is thought related to the chloride in the cis position. Cisplatin gains entry into tubular cells via uptake by the OCT-2 …

WebThe oral vinorelbine-cisplatin combination with concurrent RT is feasible and has a favorable risk-benefit ratio in stage IIIA/IIIB NSCLC. Oral vinorelbine and cisplatin with …

WebMay 27, 2024 · However, when cetuximab-based chemoradiotherapy was compared with the combination of RT and cisplatin (a crosslinking cytotoxic chemotherapy), OS, PFS, and LRC were significantly worse in unselected patients with HPV-positive oropharyngeal cancer who received cetuximab rather than cisplatin ( 4, 5 ). floor mounted urinal trapWebRadiotherapy (RT) was given concurrently with cisplatin and etoposide. G-CSF was given as primary or secondary prophylaxis or as a therapeutic measure during an episode of febrile neutropenia according to local protocols. Common terminology criteria for adverse events (CTCAE) v3.0 was used to record toxicity. ... floor mounted vanity units bathroomWebFeb 16, 2024 · severe or ongoing nausea and vomiting; vision problems, pain behind your eyes; hearing problems, ringing in your ears; pain, redness, swelling, or skin changes … great place to work-certifiedWebSep 10, 2024 · 16 pts. Dose finding study. RT to 70 Gy, 3 pts with hyperfractionated RT to 76.8 Gy. Cetuximab given with loading dose of 400-500 mg/m2 then weekly infusions of … floor mounted wall bedWebIntroduction: The aim of this multicenter phase II trial was to evaluate the combination of oral vinorelbine and cisplatin with radiotherapy (RT) after cisplatin-docetaxel induction chemotherapy (CT) in patients with locally advanced non-small cell lung cancer (NSCLC). Patients and methods: Patients with previously untreated, inoperable, histologically or … great place to work certified badgeWebCisplatin + Fluorouracil 4-6,a,b Day 1: Cisplatin 50-75mg/m 2 IV over 60 minutes b Days 1-4: Fluorouracil 1000mg/m 2 IV continuous infusion over 24 hours daily. Repeat cycle every 3 week for 3-4 ... floor mounted wall discharge toiletWebTherapeutic efficacy of cisplatin-based treatment of late stage urothelial carcinoma (UC) is limited by chemoresistance. To elucidate underlying mechanisms and to develop new approaches for overcoming resistance, we generated long-term cisplatin treated (LTT) UC cell lines, characterised their cisplatin response, and determined the expression of … floor mounted wall guards